Ajduk, Marko and Pavić, Ladislav and Bulimbašić, Stela and Šarlija, Mirko and Pavić, Predrag and Patrlj, Leonardo and Brkljačić, Boris (2009) Multidetector-row computed tomography in evaluation of atherosclerotic carotid plaques complicated with intraplaque hemorrhage. Annals of Vascular Surgery, 23 (2). pp. 186-193. ISSN 0890-5096
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Abstract
Objective: To determine sensitivity and specificity of multidetector-row computed tomography in detecting atherosclerotic carotid plaques complicated with intraplaque hemorrhage. ----- Material: Carotid plaques from 31 patients operated for carotid artery stenosis. ----- Methods: Results of preoperative multidetector-row computed tomography analysis of carotid plaques were compared with results of histological analysis of the same plaque areas. Carotid endarterectomy was performed within one week of multidetector-row computed tomography. American Heart Association classification of atherosclerotic plaques was applied for histological classification. ----- Results: Median tissue density of carotid plaques complicated with intraplaque hemorrhage was 22 Hounsfield units. Median tissue density of noncalcified segments of uncomplicated plaques was 59 Hounsfield units (p=0.0062). The highest tissue density observed for complicated plaques was 31 Hounsfield units. Multidetector-row computed tomography detected plaques complicated with hemorrhage with sensitivity of 100% and specificity of 64.7%, with tissue density of 31 Hounsfield units as a threshold value. ----- Conclusion: Multidetector-row computed tomography showed high level of sensitivity and moderate level of specificity in detecting atherosclerotic carotid plaques complicated with hemorrhage.
| Item Type: | Article | ||||||||||||||||
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| MeSH: | Aged ; Aged, 80 and over ; Carotid Stenosis/complications ; Carotid Stenosis/pathology ; Carotid Stenosis/radiography ; Carotid Stenosis/surgery ; Endarterectomy, Carotid ; Female ; Hemorrhage/etiology ; Hemorrhage/pathology ; Hemorrhage/radiography ; Hemorrhage/surgery ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Prospective Studies ; ROC Curve ; Radiographic Image Interpretation, Computer-Assisted ; Sensitivity and Specificity ; Time Factors ; Tomography, X-Ray Computed | ||||||||||||||||
| Departments: | Katedra za kirurgiju Katedra za radiologiju i opću kliničku onkologiju |
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| Depositing User: | Marijan Šember | ||||||||||||||||
| Status: | Published | ||||||||||||||||
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| Date: | March 2009 | ||||||||||||||||
| Date Deposited: | 29 Sep 2009 | ||||||||||||||||
| Last Modified: | 18 Mar 2020 12:16 | ||||||||||||||||
| Subjects: | / | ||||||||||||||||
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| URI: | http://medlib.mef.hr/id/eprint/600 |
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