Povezanost samostigme i uvida u bolest s depresivnošću i suicidalnošću u oboljelih od shizofrenije

Vidović, Domagoj (2016) Povezanost samostigme i uvida u bolest s depresivnošću i suicidalnošću u oboljelih od shizofrenije. PhD thesis, Sveučilište u Zagrebu.

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Abstract

The aim of the study was to estimate relationship of insight into the disease and internalized selfstigma on depression and suicidality. The study was conducted using cross-sectional method among 149 patients diagnosed with schizophrenia who were treated at the University Psychiatric Hospital Vrapče in Zagreb, July 2012 to December 2014. The diagnosis of schizophrenia was set by two independent psychiatrists according to diagnostic criteria of ICD-10 and DSM-IV. For each patient socio-demographic and hospital data were gathered. Observed clinical features were objectified using PANSS, CGI, ISMI (Internalized stigma in Mental Illness), SUMD (Scale to Assess Unawareness of Mental Disorder), CDSS (Calgary Depression Scale for Schizophrenia), ISST (InterSePT Scale for Suicidal Thinking), BCS (Beck's Hopelessness Scale), and WHOQOL-BREF (WHO Quality of Life-BREF). Regarding insight into illness statistically significant difference was found between in the intensity of psychopathology, general clinical impression, depression, suicidality, hopelessness and quality of life. Regarding internalized selfstigma statistically significant difference was found between in the intensity of psychopathology, general clinical impression, depression, suicidality, hopelessness and quality of life. The study confirmed hypothesis that internalized selfstigma moderates relationship between better insight into illness and depression. The hypothesis that greater insight into the disease and internalized selfstigma has an impact on depression, suicide, hopelessness and lower quality of life. Moderating role of internalized selfstigma on relationship between insight into illness and suicidality was not found.

Abstract in Croatian

Cilj istraživanja bila je procjena povezanosti uvida u bolest i internalizirane samostigme na depresivnost i suicidalnost kod oboljelih od shizofrenije. Istraživanje je provedeno presječnom studijom među 149 bolesnika s dijagnozom shizofrenije koji su liječeni u Psihijatrijskoj bolnici Vrapče u Zagrebu, u periodu od 1. srpnja 2012. godine do 1. prosinca 2014. godine. Dijagnoza shizofrenije postavljena je po dva neovisna psihijatra, sukladno dijagnostičkim kriterijima MKB-10 i DSM-IV. Za svakog pojedinog pacijenta iz uzorka, prikupljena su sociodemografska i hospitalna obilježja. Promatrana klinička obilježja objektivizirana su pomoću PANSS, CGI, ISMI (Internalized Stigma of Mental Illness), SUMD (Scale to Assess Unawareness of Mental Disorder), CDSS (Calgary Depression Scale for Schizophrenia), ISST (InterSePT Scale for Suicidal Thinking), BHS (Beck's Hopelessness Scale), WHOQOL-BREF (WHO Quality of Life-BREF). U odnosu na uvid u bolest nađena je statistički značajna razlika u intenzitetu psihopatologije, opće kliničke impresije, depresivnosti, suicidalnosti, beznadnosti i kvalitete života. U odnosu na internaliziranu samostigmu utvrđena je statistički značajna razlika u intenzitetu psihopatologije, suicidalnosti, depresivnosti, beznadnosti i kvalitete života. Istraživanjem je potvrđena hipoteza kako internalizirana samostigma moderira povezanost boljeg uvida u bolest i depresivnosti. Potvrđena je hipoteza kako bolji uvid u bolest i internalizirana samostigma imaju utjecaj na depresivnost, suicidalnost, beznadnost i nižu kvalitetu života. Nije potvrđena moderatorska uloga internalizirane samostigme na povezanost uvida u bolest i suicidalnosti.

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