Extramedullary plasmacytoma imitating neoplasm of the gallbladder fossa after cholecystectomy [Ekstramedularni plazmocitom koji imitira tumor lože žućnjaka nakon učinjene kolecistektomije]

Majerović, Matea and Bogdanić, Branko and Drinković, Nikša and Bašić Kinda, Sandra and Jakić-Razumović, Jasminka and Gašparović, Vladimir (2012) Extramedullary plasmacytoma imitating neoplasm of the gallbladder fossa after cholecystectomy [Ekstramedularni plazmocitom koji imitira tumor lože žućnjaka nakon učinjene kolecistektomije]. Collegium Antropologicum, 36 (1). pp. 331-333. ISSN 0350-6134

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Abstract

Extramedullary plasmacytomas are plasma cell tumors that arise outside of the bone marrow. They account for approximately 3% of plasma cell neoplasms and are most frequently located in the head and neck region. Five months after undergoing cholecystectomy, a 69-year-old patient presented with the pain under the right costal margin and a 12 kg weight loss. Computed tomography of the abdomen demonstrated irregular, vascular mass in the gallbladder fossa that dents towards the duodenum and the pylorus and lowers caudally to the hepatic flexure. His laboratory tests indicated normocytic anemia and showed elevated sedimentation rate. During operative procedure, a tumorous mass in the gallbladder fossa was found, inseparable of the peritoneum of the hepatoduodenal ligament and the IVb liver segment. Histopathological examination and immunohistochemical staining determined the diagnosis of the plasmacytoma. Total resection of the tumor was achieved and after 24-month follow-up patient showed no signs of local recurrence or dissemination of the disease.

Abstract in Croatian

Ekstramedularni plazmocitomi su rijetki tumori plazma stanica, najčešće lokalizirani u regiji glave i vrata. Pet mjeseci nakon što je bio podvrgnut kolecistektomiji, 69-godišnji pacijent se prezentirao sa bolovima pod desnim rebrenim lukom i gubitkom na težini od 12 kg. CT abdomena je pokazao nepravilnu, vaskulariziranu tvorbu u loži žućnog mjehura koja se protezala prema duodenumu i pylorusu te spuštala kaudalno do hepatalne fleksure. Njegovi laboratorijski nalazi su ukazivali na normocitnu anemiju i povišenu sedimentaciju eritrocita. Tijekom operativnog postupka nađena je tumorozna tvorba u loži žućnog mjehura neodvojiva od peritoneuma hepatoduodenalnog ligamenta i IVb segmenta jetre. Histopatološkim nalazom i imunohistokemijskim bojenjem postavljena je dijagnoza plazmocitoma. Postignuta je potpuna resekcija tumorskog tkiva te nakon 24 mjeseci praćenja bolesti pacijent ne pokazuje znakove lokalnog recidiva ili diseminacije bolesti.

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