Repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Homocystinuria, a possible solution of the Akhenaten's mystery

Čavka, Mislav and Kelava, Tomislav and Čavka, Vlatka and Bušić, Željko and Olujić, Boris and Brkljačić, Boris (2010) Homocystinuria, a possible solution of the Akhenaten's mystery. Collegium Antropologicum, 34 (Suppl.). pp. 255-8. ISSN 0350-6134

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    Croatian abstract

    HOMOCISTINURIJA, MOGUĆE RJEŠENJE EHNATONOVE TAJNE ----- Faraon Amenofis IV. (Amenhotep IV.), poznatiji kao Ehnaton, najtajnovitija je osoba u egipatskoj povijesti. Ovaj revolucionarni vladar 18. dinastije proveo je vjersku revoluciju i postavio nove standarde u umjetnosti. Ostaje nejasno je li groteskni prikaz njega i njegove obitelji samo umjetnički odmak od staroegipatskog kanona ili vrhunski paleopatološki priručnik. Da bi se objasnio njegov izgled, dosad je predloženo nekoliko bolesti od kojih je mogao bolovati, ali ni jedna nije u potpunosti prihvatljiva. Mi predlažemo novu bolest; homocistinuriju – manjak cistationin-sintaze. Zaključujemo da u usporedbi sa dosad najboljom teorijom – da je Ehnaton bolovao od Marfanovog sindroma, naša teorija jednako dobro objašnjava njegov izgled, ali bolje objašnjava zahvaćenost odnosno nezahvaćenost njegovih rođaka. Ovo je jedina teorija o Ehnatonovoj bolesti koja bi mogla biti provjerena u bliskoj budućnosti.

    English abstract

    Pharaoh Amenophis IV (Amenhotep IV), also known as Akhenaten, is the most mysterious person in Egyptian history and he still remains the object of academic argues. This revolutionary king introduced a new concept in Egyptian religion and arts. It is still unexplained if images of him and his family were just an artistic outbreak from old Egyptian canon or an excellent paleopathological study. Several pathologic conditions were proposed to explain his appearance but neither is completely acceptable. We propose a different disease that he could have suffered of: homocystinuria – lack of cysthationine-synthase. Our conclusion is that in comparison with up to date most convincing theory, that he was suffering of Marfan syndrome, our theory equally well explains his physical appearance but is better in explaining affecting and unaffecting of his relatives. This is the only theory about Akhenaten’s disease that could be checked in the near future.

    Item Type: Article
    MeSH: Egypt ; Famous Persons ; History, Ancient ; Homocystinuria/genetics ; Homocystinuria/history ; Humans ; Paleopathology
    Divisions: Katedra za radiologiju i opću kliničku onkologiju
    Depositing User: Marijan Šember
    Status: Published
    Creators:
    CreatorsEmail
    Čavka, Mislav
    Kelava, Tomislav
    Čavka, Vlatka
    Bušić, Željko
    Olujić, Boris
    Brkljačić, Boris
    Date: March 2010
    Date Deposited: 07 Jun 2010
    Last Modified: 23 Sep 2011 18:11
    Subjects: /
    Related URLs:
      URI: http://medlib.mef.hr/id/eprint/810

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