Repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Multidetector-row computed tomography in evaluation of atherosclerotic carotid plaques complicated with intraplaque hemorrhage

Ajduk, Marko and Pavić, Ladislav and Bulimbašić, Stela and Šarlija, Mirko and Pavić, Predrag and Patrlj, Leonardo and Brkljačić, Boris (2009) Multidetector-row computed tomography in evaluation of atherosclerotic carotid plaques complicated with intraplaque hemorrhage. Annals of Vascular Surgery, 23 (2). pp. 186-193. ISSN 0890-5096

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    English abstract

    Objective: To determine sensitivity and specificity of multidetector-row computed tomography in detecting atherosclerotic carotid plaques complicated with intraplaque hemorrhage. ----- Material: Carotid plaques from 31 patients operated for carotid artery stenosis. ----- Methods: Results of preoperative multidetector-row computed tomography analysis of carotid plaques were compared with results of histological analysis of the same plaque areas. Carotid endarterectomy was performed within one week of multidetector-row computed tomography. American Heart Association classification of atherosclerotic plaques was applied for histological classification. ----- Results: Median tissue density of carotid plaques complicated with intraplaque hemorrhage was 22 Hounsfield units. Median tissue density of noncalcified segments of uncomplicated plaques was 59 Hounsfield units (p=0.0062). The highest tissue density observed for complicated plaques was 31 Hounsfield units. Multidetector-row computed tomography detected plaques complicated with hemorrhage with sensitivity of 100% and specificity of 64.7%, with tissue density of 31 Hounsfield units as a threshold value. ----- Conclusion: Multidetector-row computed tomography showed high level of sensitivity and moderate level of specificity in detecting atherosclerotic carotid plaques complicated with hemorrhage.

    Item Type: Article
    MeSH: Aged ; Aged, 80 and over ; Carotid Stenosis/complications ; Carotid Stenosis/pathology ; Carotid Stenosis/radiography ; Carotid Stenosis/surgery ; Endarterectomy, Carotid ; Female ; Hemorrhage/etiology ; Hemorrhage/pathology ; Hemorrhage/radiography ; Hemorrhage/surgery ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Prospective Studies ; ROC Curve ; Radiographic Image Interpretation, Computer-Assisted ; Sensitivity and Specificity ; Time Factors ; Tomography, X-Ray Computed
    Divisions: Katedra za radiologiju i opću kliničku onkologiju
    Katedra za kirurgiju
    Depositing User: Marijan Šember
    Status: Published
    Creators:
    CreatorsEmail
    Ajduk, Markomajduk@yahoo.com
    Pavić, Ladislav
    Bulimbašić, Stela
    Šarlija, Mirko
    Pavić, Predrag
    Patrlj, Leonardo
    Brkljačić, Boris
    Date: March 2009
    Date Deposited: 29 Sep 2009
    Last Modified: 23 Sep 2011 18:10
    Subjects: /
    Related URLs:
      URI: http://medlib.mef.hr/id/eprint/600

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