Repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Large volume leukapheresis: Efficacy and safety of processing patient's total blood volume six times

Bojanić, Ines and Dubravčić, Klara and Batinić, Drago and Golubić Ćepulić, Branka and Mazić, Sanja and Hren, Darko and Nemet, Damir and Labar, Boris (2011) Large volume leukapheresis: Efficacy and safety of processing patient's total blood volume six times. Transfusion and Apheresis Science, 44 (2). pp. 139-47. ISSN 1473-0502

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    English abstract

    Large-volume leukapheresis (LVL) differs from standard leukapheresis by increased blood flow and an altered anticoagulation regimen. An open issue is to what degree a further increase in processed blood volume is reasonable in terms of higher yields and safety. In 30 LVL performed in patients with hematologic malignancies, 6 total blood volumes were processed. LVL resulted in a higher CD34+ cell yield without a change in graft quality. Although a marked platelet decrease can be expected, LVL is safe and can be recommended as the standard procedure for patients who mobilize low numbers of CD34+ cells and when high number of CD34+ cells are required.

    Item Type: Article
    Divisions: Katedra za fiziologiju i imunologiju
    Katedra za internu medicinu
    Depositing User: Marijan Šember
    Status: Published
    Creators:
    CreatorsEmail
    Bojanić, Ines
    Dubravčić, Klara
    Batinić, Drago
    Golubić Ćepulić, Branka
    Mazić, Sanja
    Hren, Darko
    Nemet, Damir
    Labar, Boris
    Date: April 2011
    Date Deposited: 20 Apr 2011
    Last Modified: 23 Sep 2011 18:11
    Subjects: /
    Related URLs:
      URI: http://medlib.mef.hr/id/eprint/981

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