Epitheloid hemangioendothelioma in patient with liver transplantation

Filipec Kanižaj, Tajana and Čolić Cvrlje, Vesna and Mrzljak, Anna and Kardum-Skelin, Ika and Šušterčić, Dunja and Škegro, Dinko and Guštin, Denis and Kocman, Branislav (2010) Epitheloid hemangioendothelioma in patient with liver transplantation. Collegium Antropologicum, 34 (1). pp. 177-80. ISSN 0350-6134

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Abstract

Malignant hepatic epithelioid hemangioendothelioma (HEH) is a rare malignant tumor of vascular origin with unknown aetiology and a variable natural course. At the time of diagnosis, most patients present with multifocal tumours lesions that involve both liver lobes. From the therapeutic aspect, liver resection (LRx), liver transplantation (LTx), chemotherapy, radiotherapy, and/or immunotherapy have been used in the treatment of patients with HEH. However, because of the rarity of this tumor and its unpredictable natural history, it is impossible to assess the effectiveness of these respective therapies. In this report, our objective was to present clinical aspects, diagnostic options, therapeutic modalities, and the clinical outcome of single patient with LTx because of this rare tumor.

Abstract in Croatian

EPITELOIDNI HAEMAGIOTELIOM U BOLESNIKA S TRANSPLANTACIJOM JETRE ----- Maligni epiteloidni hemangioendoteliom jetre je rijetki maligni tumor porijeklom od stanica krvnih žila s nepoznatom etiologijom i varijabilnim prirodnim tijekom. U vrijeme postavljanja dijagnoze većina bolesnika prezentira se s multifokalnim tumorskim promjenama koje zahvaćaju oba režnja jetre. U terapiji provode se postupci resekcije dijela jetre, transplantacije jetre, kemoterapije, zračenja i/ili imunomodulatorne terapije. Obzirom na rijetkost navedenog tumora i nepredvidiv prirodni tijek bolesti nemoguće je generalno procijeniti efektivnost navedenih terapija. U ovom prikazu cilj je prikazati kliničke aspekte, dijagnostičke mogućnosti, terapijske modalitete i tijek bolesti kod bolesnice s transplantiranom jetrom uslijed navedenog rijetkog tumora.

Item Type: Article
MeSH: Antigens, CD31/metabolism ; Antigens, CD34/metabolism ; Biopsy, Fine-Needle ; Eosine Yellowish-(YS) ; Female ; Hemangioendothelioma, Epithelioid/metabolism ; Hemangioendothelioma, Epithelioid/pathology ; Hemangioendothelioma, Epithelioid/surgery ; Humans ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Liver Neoplasms/surgery ; Liver Transplantation ; Methylene Blue ; Middle Aged
Departments: Katedra za internu medicinu
Depositing User: Marijan Šember
Status: Published
Creators:
CreatorsEmail
Filipec Kanižaj, TajanaUNSPECIFIED
Čolić Cvrlje, VesnaUNSPECIFIED
Mrzljak, AnnaUNSPECIFIED
Kardum-Skelin, IkaUNSPECIFIED
Šušterčić, DunjaUNSPECIFIED
Škegro, DinkoUNSPECIFIED
Guštin, DenisUNSPECIFIED
Kocman, BranislavUNSPECIFIED
Date: March 2010
Date Deposited: 11 Jun 2010
Last Modified: 23 Sep 2011 16:11
Subjects: /
Related URLs:
    URI: http://medlib.mef.hr/id/eprint/787

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