Prostatic carcinoma metastatic to the optic nerve [Metastaza karcinoma postate u vidnom živcu]

Cerovski, Branimir and Vidović, Tomislav and Stiglmayer, Neda and Popović Suić, Smiljka (2009) Prostatic carcinoma metastatic to the optic nerve [Metastaza karcinoma postate u vidnom živcu]. Collegium Antropologicum, 33 (4). pp. 1421-2. ISSN 0350-6134

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Abstract

Optic nerve can be infiltrated with various tumors and inflammatory processes, with a considerable prevalence of primary over secondary tumors. Metastases of gastric carcinoma to the optic nerve are less frequently, and those of prostatic carcinoma very infrequently observed. A 66 year-old man presented with metastasis to the optic nerve with consequential vision loss to the level of light perception developed two years after prostatic surgery. Systemic therapy with methylprednisolone resulted in a satisfactory vision function recovery. According to literature data, prostatic carcinoma metastases to the optic nerve occur very rarely. In our patient with the optic nerve infiltration found on the first clinical examination, papillary edema was associated with the signs of optic nerve functional impairment (visual acuity, visual field, unilateral RAPD). An infiltrative process involving a distal portion of the optic nerve usually does not cause papillary alterations, and produces a clinical picture of retrobulbar optic neuropathy, such as that observed in our patient on the second clinical examination, showing the signs of optic nerve damage.

Abstract in Croatian

Optički živac može biti infiltriran različitim tumorima i upalnim pocesima, s većom učestalošću primarnih tumora. Metastaze karcinoma želuca, a poglavito prostate vrlo su rijetke. Cilj ovoga rada je prikazati 66 godišnjeg muškarca u kojeg se metastaza vidnog živca manifestirala 2 godine nakon operacije prostate s edemom glave vidnog živca i posljedičnim oštećenjem vida. Sustavna steroidna terapija dovela je do oporavka vidne funkcije. Treba istaknuti da je prikazan bolesnik s rijetkim oblikom sekundarne tumorske infiltracije vidnog živca, u kojeg je nađen edem glave vidnog živca praćen znacima oštećenja vidne fukcije (vidna oštrina, vidno polje, RAPD). Kada infiltrativni proces zahvati distalni dio vidnog živca ne nastaje edem papile, ali su prisutni znaci retrobulbarne optičke neuropatije.

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