Fetal macrosomia in pregnant women with gestational diabetes [Fetalna makrosomija u trudnica s gestacijskim dijabetesom]

Šegregur, Jadranko and Buković, Damir and Milinović, Darko and Orešković, Slavko and Pavelić, Jasminka and Župić, Tomislav and Peršec, Jasminka and Pavić, Mato (2009) Fetal macrosomia in pregnant women with gestational diabetes [Fetalna makrosomija u trudnica s gestacijskim dijabetesom]. Collegium Antropologicum, 33 (4). pp. 1121-1127. ISSN 0350-6134

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Abstract

The aim of the study was to determine the frequency of fetal macrosomia in newborns from mothers with gestational diabetes mellitus (GDM) and healthy mothers, as well as determining the influence of fetal growth on pregnancy termination, on complications in pregnancy, during delivery and puerperium and on neonatal complications. In the study were included 351 pregnant women with GDM, as well as control group of 1502 healthy pregnant women. Newborns of mothers with GDM had significantly higher birth weight and length, ponderal index >2.85 was more frequent, they were macrosomic and hypertrophic (disproportional and proportional), had smaller Apgar score and more frequent neonatal complications (p<0.05). Fetal macrosomia and fetal hypertrophy alone or, particularly, connected with disproportional fetal growth, but disproportional hypotrophy as well, had significantly influence on greater frequency of delivery and puerperal complications, delivery completion with Cesarean section and neonatal complications in pregnant women with GDM.

Abstract in Croatian

Cilj rada je bio utvrditi učestalost fetalne makrosomije u novorođenčadi rođenih od majki koje boluju od gestacijskog dijabetesa melitusa (GDM) i zdravih majki, kao i utjecaj fetalnog rasta na način dovršenja trudnoće i učestalost komplikacija u trudnoći, porodu i puerperiju, te neonatalnih komplikacija. U istraživanje je uključeno 351 trudnica s GDM i 1502 zdrave trudnice kao kontrolna skupina. Novorođenčad trudnica s GDM su značajno veće porodne težine i duljine, učestalijeg PI>2,85, makrosomna su i hipertrofična (disproporcionalno i proporcionalno), imaju manje vrijednosti Apgar indeksa i veću učestalost neonatalnih komplikacija. (p<0,05). Fetalna makrosomija i fetalna hipertrofija same, posebice udružene s disproporcionalnim fetalnim rastom, ali i disproporcionalna hipotrofija, imaju značajan utjecaj na povećanu učestalost komplikacija u porodu i puerperiju, dovršenja poroda SC i neonatalnih komplikacija u trudnica s GDM.

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