Repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Psychoeducation versus treatment as usual in diabetic patients with subthreshold depression: preliminary results of a randomized controlled trial

Pibernik-Okanović, Mirjana and Begić, Dražen and Ajduković, Dea and Andrijašević, Nataša and Metelko, Željko (2009) Psychoeducation versus treatment as usual in diabetic patients with subthreshold depression: preliminary results of a randomized controlled trial. Trials, 10 (78). ISSN 1745-6215 (Electronic)

[img]
Preview
PDF
Download (622Kb) | Preview

    English abstract

    BACKGROUND ----- Research on the effects of treating sub-threshold depression in persons with diabetes is scarce in spite of the findings indicating that this condition is highly prevalent in the diabetic population and may increase the risk of developing a subsequent major depression. This study was aimed at exploring the effects of a psycho-educational intervention on depression- and diabetes-related outcomes in patients with mild to moderate depressive symptoms. METHODS ----- A randomized controlled study design with a one-year follow-up was used. Fifty patients with mild to moderate depressive symptoms (74% female, aged 57 +/- 9 yrs, diabetes duration of 10 +/- 8 yrs, BMI 31 +/- 6 kg/m2, HbA1C 7.7% +/- 1.4, 53% insulin treated) were randomly assigned to either an intervention or a control group. The intervention group underwent four psycho-educational sessions aimed at enabling self-management of depressive symptoms. The control group was informed about the screening results and depression treatment options while continuing diabetes treatment as usual. Both groups were contacted by phone in 2-3-month intervals, and re-assessed for depression after 6 and 12 months. Changes in depressive symptoms and glycaemic control were considered primary outcomes. Mann-Whitney U test and Friedman ANOVA were used to compare between- and within-group indicators at 6- and 12-month follow-ups. RESULTS ----- Both the intervention and the control group reported a significant decrease in depressive symptoms as measured by the CES-D scale (Friedman ANOVA chi2 = 10.8 p = .004 and chi2 = 7.3 p = 0.03, respectively). The 6-month and 1-year indicators of glycaemic control as compared to baseline HbA1C values were also improved in both groups (chi2 = 11.6 p = 0.003 and chi2 = 17.1 p = 0.0002, respectively). Between-group differences in depressive symptoms and HbA1C values were not statistically significant either at 6- or at 12-month follow-up (all p > 0.05).CONCLUSION ----- Psycho-educational treatment appears to be beneficial in diabetic patients with mild to moderate depressive symptoms, but its effects are comparable with the non-specific support given to the subjects in the control group. TRIAL REGISTRATION ----- Current Controlled Trials ISRCTN58745372.

    Item Type: Article
    Divisions: Katedra za internu medicinu
    Katedra za psihijatriju i psihološku medicinu
    Depositing User: Marijan Šember
    Status: Published
    Creators:
    CreatorsEmail
    Pibernik-Okanović, Mirjana
    Begić, Dražen
    Ajduković, Dea
    Andrijašević, Nataša
    Metelko, Željko
    Date: 26 August 2009
    Date Deposited: 02 Oct 2009
    Last Modified: 07 Feb 2013 10:32
    Subjects: /
    Related URLs:
      URI: http://medlib.mef.hr/id/eprint/678

      Actions (login required)

      View Item

      Document Downloads

      More statistics for this item...