Repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Paget's disease in contralateral breast occuring 11 years after mastectomy for invasive ductal carcinoma

Salopek, Daniela and Murgić, Jure and Tomas, Davor and Bolanča, Ante and Kusić, Zvonko (2009) Paget's disease in contralateral breast occuring 11 years after mastectomy for invasive ductal carcinoma. Collegium antropologicum, 33 (1). pp. 327-329. ISSN 0350-6134

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    Croatian abstract

    POJAVA PAGETOVE BOLESTI U KONTRALATERALNOJ DOJCI 11 GODINA NAKON MASTEKTOMIJE ZBOG DUKTALNOG INVAZIVNOG KARCINOMA ----- Pagetova bolest dojke je rijedak oblik karcinoma dojke koji predstavlja 1–4% svih zloćudnih tumora dojke. Karakterizirana je prisutnošću Pagetovih stanica u epidermisu i predstavlja leziju bradavice. U većini je slučajeva Pagetova bolest povezana sa pridruženim podležećim karcinomom dojke. Mastektomija se smatra liječenjem izbora, ali se poštedni kirurški zahvat također primjenjuje u pravilno izabranih bolesnica, ovisno o podležećoj malignosti. Prikazujemo slučaj pojave Pagetove bolesti u kontralateralnoj dojci, bez pridruženog maligniteta dojke, 11 godina nakon mastektomije zbog duktalnog invazivnog karcinoma.

    English abstract

    Paget's disease of the breast is a rare form of breast cancer and represents only 1% to 4% of all breast cancers. It is characterized by the presence of Paget's cells in the epithelium tissue (in epidermis) and it manifests as a lesion of the nipple. In most cases, Paget's disease is associated with an underlying breast malignancy. Mastectomy has been considered the treatment of choice, but breast conservation is also being explored, in properly selected patients, depending on the underlying malignancy. We report a case of Paget's disease occurring in the contralateral breast 11 years after mastectomy for invasive ductal carcinoma but with no underlying breast malignancy.

    Item Type: Article
    MeSH: Aged ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Carcinoma, Ductal, Breast/surgery ; Female ; Humans ; Immunohistochemistry ; Mastectomy ; Paget's Disease, Mammary/pathology ; Receptor, erbB-2/analysis
    Divisions: Katedra za radiologiju i opću kliničku onkologiju
    Depositing User: Marijan Šember
    Status: Published
    Creators:
    CreatorsEmail
    Salopek, Daniela
    Murgić, Jure
    Tomas, Davor
    Bolanča, Ante
    Kusić, Zvonko
    Date: March 2009
    Date Deposited: 31 Aug 2009
    Last Modified: 23 Sep 2011 18:11
    Subjects: /
    Related URLs:
      URI: http://medlib.mef.hr/id/eprint/639

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