Repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Sex or surgery - erectile dysfunction after radical treatment of localized prostate cancer

Lesko Kelović, Vesna and Buković, Damir and Badžek, Saša and Curić, Zvonimir and Kelović, Zlatko and Peršec, Zoran and Pavić, Mato (2009) Sex or surgery - erectile dysfunction after radical treatment of localized prostate cancer. Collegium antropologicum, 33 (2). pp. 529-532. ISSN 0350-6134

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    Croatian abstract

    SEKS ILI KIRURGIJA – EREKTILNA DISFUNKCIJA NAKON RADIKALNOG LIJEČENJA LOKALIZIRANOG RAKA PROSTATE ----- Očuvanje odgovarajuće kvalitete života je vrlo bitno bolesnicima koji se liječe od lokaliziranog raka prostate. Proveli smo studiju presjeka kako bi utvrdili seksualnu funkciju nakon radikalne prostatektomije (RP) i eksterne radioterapije (ER). U istraživanje je uključeno 57 bolesnika sa ranim karcinomom prostate koji su liječeni u našoj ustanovi od siječnja 2003. godine do prosinca 2003. godine. Trideset i tri bolesnika su liječena radikalnom retropubičnom prostatektomijom, a 24 primarnom radikalnom radioterapijom. Bolesnici su ispunili međunarodni upitnik za indeks erektilne funkcije 2 do 4 mjeseca i 6 mjeseci nakon liječenja. Postterapijska seksualna funkcija je kod bolesnika koji su liječeni ER značajno bolja u odnosu na skupinu liječenu sa RP (48,5% vs. 21,57%, p<0,0001). Dodatne analize su pokazale da je kod bolesnika liječenih sa ER zadovoljstvo erektilnom funkcijom, sposobnost održavanja spolnog odnosa i mogućnost ejakulacije bolja u odnosu na one liječene RP (44,67% vs. 11,57%, p <0,0001), te također i opća kvaliteta spolnog života (48,5% u ER grupi vs. 21,57% u RP grupi, p <0,0001). Interes za seksualne odnose bio je naprotiv podjednak kod obje skupine bolesnika Erektilna funkcija je 6 mjeseci nakon kirurškog ili radioterapijskog liječenja ranog karcinoma prostate gotovo dva puta lošija kod bolesnika liječenih RP u odnosu na one liječenja ER.

    English abstract

    The maintenance of satisfactory quality of life is major concern in majority of patients who elect treatment for localized prostate cancer. We conducted a cross-sectional study to determine sexual function after radical prostatectomy (RP) and external beam radiotherapy (EBRT). Study population consisted of series of 57 patients with early-stage adenocarcinoma of the prostate, treated in our institution in the period from January 2003 till December 2003. Thirty three patients underwent radical retropubical prostatectomy and 24 patients were treated by primary radical radiotherapy. Patients have been given the full international index of erectile function (IIEF) questionnaire two to four and six months after the treatment. Post treatment sexual function in patients treated by EBRT is significantly better than in patients treated by RP (48.5% vs. 21.57%, p < 0.0001). Subgroup analysis reveals that satisfaction with erectile function, maintaining of sexual intercourse and possibility of ejaculation is better in patients treated by EBRT than in patients treated by RP (44.67% vs. 11.57%, p < 0.0001) as well as general satisfaction with quality of sexual life (48.5% in EBRT group vs. 21.57% in RP group, p < 0.0001). On the other hand, sexual desire remains the same in both groups of patients (63.75% in EBRT group vs. 60.61% in RP group, p = 0.71). Six months after surgical or radiotherapy treatment erectile function is almost as twice as worse in patients treated by surgery than in patients treated by radiotherapy.

    Item Type: Article
    MeSH: Aged ; Comorbidity ; Cross-Sectional Studies ; Erectile Dysfunction/epidemiology ; Humans ; Incidence ; Male ; Postoperative Complications/epidemiology ; Prostatectomy/statistics & numerical data ; Prostatic Neoplasms/epidemiology ; Prostatic Neoplasms/radiotherapy ; Prostatic Neoplasms/surgery ; Quality of Life ; Recovery of Function
    Divisions: Katedra za anatomiju i kliničku anatomiju
    Katedra za ginekologiju i opstetriciju
    Depositing User: Marijan Šember
    Status: Published
    Creators:
    CreatorsEmail
    Lesko Kelović, Vesna
    Buković, Damir
    Badžek, Saša
    Curić, Zvonimir
    Kelović, Zlatko
    Peršec, Zoran
    Pavić, Mato
    Date: June 2009
    Date Deposited: 23 Sep 2009
    Last Modified: 23 Sep 2011 18:11
    Subjects: /
    Related URLs:
      URI: http://medlib.mef.hr/id/eprint/635

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