Dupuytren's disease characteristics in Primorsko-goranska County, Croatia

Jurišić, Davor and Ković, Ivor and Lulić, Ileana and Stanec, Zdenko and Kapović, Miljenko and Uravić, Miljenko (2008) Dupuytren's disease characteristics in Primorsko-goranska County, Croatia. Collegium Antropologicum, 32 (4). pp. 1209-1213. ISSN 0350-6134

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Abstract

Dupuytren's disease predominantly occurs among Europeans, with higher reported prevalence in Northern than in Mediterranean European countries. We evaluated the recurrence and extension rates among Caucasian patients from Primorsko-goranska County in Croatia who underwent partial fasciectomy as treatment for Dupuytren's disease. Furthermore, we investigated the influence of diathesis factors on disease progression. Recurrent disease was observed in 68 out of 93 patients (73%). There where 48 (52%) patients with extension of the disease. Differences were found between patients with recurrent disease and those without recurrence regarding age at onset, age at operation and duration of disease. We compared patients younger and older than 50 years at disease onset, and found that older patients had a significantly higher recurrence rate. Characteristics of our patients fit into the picture of typical Dupuytren's disease except for the influence of early age at onset. Among our patients late age at onset proved to be a diathesis factor.

Abstract in Croatian

Dupuytrenova kontraktura dominantno se javlja u Europljana, s višom prevalencijom u zemljama smještenim na sjeveru Europe. Cilj naše studije bio je procijeniti stupanj recidiva i ekstenzije Dupuytrenove kontrakture u pacijenata iz Primorsko-goranske županije liječenih u Kliničkom Bolničkom Centru Rijeka. Nadalje, željeli smo ispitati utjecaj čimbenika dijateze na progresiju bolesti. Recidiv je primjećen u 68 (73%), a ekstenzija bolesti u 48 (52%) od ukupno 93 pacijenta. Značajne razlike su opažene između pacijenata s recidiviom i onih bez recidiva s obzirom na dob pojave bolesti, dob pri operaciji i duljini trajanja bolesti. Usporedba pacijenata mlađih i starijih od 50 godina pokazala je značajno viši stupanj recidiva u starijih pacijenata. Karakteristike naših pacijenata uklapaju se u tipičnu sliku Dupuytrenove kontrakture, uz izostanak očekivanog utjecaja rane pojave bolesti na stupanj recidiva i ekstenzije. Upravo suprotno, pojava bolesti u kasnijoj životnoj dobi pokazala se kao čimbenik dijateze.

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