Seroprevalence of Helicobacter pylori infection in dyspeptic patients

Marušić, Marinko and Presečki, Vladimir and Katičić, Miroslava and Bilić, Ante and Jurčić, Dragan and Schwarz, Dragan (2008) Seroprevalence of Helicobacter pylori infection in dyspeptic patients. Collegium Antropologicum, 32 (4). pp. 1149-1153. ISSN 0350-6134

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Abstract

The objective of the study was to assess the effect of age on the seroprevalence of Helicobacter (H.) pylori infection in dyspeptic patients. The results obtained in the patient group were compared with findings on the seroprevalence of H. pylori infection in 2051 blood donors. Serum samples were tested by the commercial ELISA and CFT assays according to manufacturer's instructions. The mean seroprevalence of H. pylori infection as determined by ELISA/CFT was 64.0%/51.7% in the group of blood donors and 92.3%/89.5% in the group of dyspeptic patients. Study results indicated a higher prevalence of H. pylori infection in dyspeptic patients as compared with blood donors in all age groups. In the patient S group, H. pylori seroprevalence was not age dependent.

Abstract in Croatian

Ovim radom željeli smo utvrditi utjecaj životne dobi na seroprevalenciju infekcije Helicobacter pylori kod bolesnika s dispeptičnim tegobama. Dobivene nalaze usporedili smo s nalazima seroprevalencije ove infekcije u 2051 dobrovoljnog darovatelja krvi. Uzorci seruma testirani su komercijalnim pripravcima ELISA i CFT prema uputama proizvođača. U skupini dobrovoljnih darovatelja krvi prosječna seroprevalencija infekcije bila je 64,0%/51,7% (ELISA/CFT), a u skupini bolesnika s dispeptičnim tegobama 92,3%/89,5% (ELISA/CFT). Rezultati rada ukazuju na veću učestalost infekcije H. pylori u bolesnika nego kod dobrovoljnih darovatelja krvi po svim dobnim skupinama, a u skupini bolesnika je utvrđeno da seroprevalencija H. pylori ne ovisi o životnoj dobi.

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