Lower gastrointestinal disorders in patients with irritable bowel syndrome

Jurčić, Dragan and Bilić, Ante and Schwarz, Dragan and Luetić, Krešimir and Marušić, Marinko and Včev, Aleksandar and Gabrić, Maruška and Špoljarić, Ljubica (2008) Lower gastrointestinal disorders in patients with irritable bowel syndrome. Collegium antropologicum, 32 (3). pp. 755-759. ISSN 0350-6134 (Print)

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Abstract

Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal system characterized by abdominal pain related to bowel emptying, defecation impairment and abdominal distention. The aim of the study was to objectify lower gastrointestinal system disturbances in IBS patients. Thirty IBS patients and 30 healthy subjects were included in the study. IBS patients were divided into two subgroups: IBS with predominant diarrhea (IBSd) and IBS with predominant constipation (IBSc). All study subjects underwent physical examination (including digitorectal examination), standard laboratory testing and anorectal manometry. Endoscopy was performed only in group of IBS patients. A statistically significant difference was recorded in most manometric parameters between healthy subjects and IBS patients, which was even more pronounced in IBSd patients. Study results showed that the intestinal motility disorder underlying IBS could be objectified by use of anorectal manometry.

Abstract in Croatian

Sindrom iritabilnog crijeva (SIC) funkcijski je poremećaj probavnog sustava koji karakterizira bol u abdomenu povezana sa defekacijom, poremećaji defekacije te distenzija trbuha. Našim istraživanjem željeli smo objektivizirati promjene u donjim dijelovima gastrointestinalnog trakta u bolesnika sa sindromom iritabilnog crijeva. U istraživanje je uključeno trideset bolesnika sa SIC i 30 zdravih ispitanika. Bolesnici sa SIC podijeljeni su u dvije podskupine: prva (SICp) s predominantnim proljevom i druga (SICk) s dominantnom konstipacijom. Svim ispitanicima učinjen je fizikalni pregled (uključujući digitorektalni), standardno laboratorijsko testiranje, anorektalna manometrija, a bolesnicima sa SIC i endoskopija. Rezultati su pokazali da postoji statistički značajna razlika u većini manometrijskih parametara u bolesnika sa SIC, dok je razlika još izraženija u bolesnika sa SICp. Naše istraživanje pokazuje da upotrebljavajući anorektalnu manometriju možemo objektivizirati poremećaj motiliteta crijeva koji i jest u podlozi SIC-a.

Item Type: Article
MeSH: Lower Gastrointestinal Tract ; Gastrointestinal Diseases - diagnosis - etiology - physiopathology ; Irritable Bowel Syndrome - complications - diagnosis ; Adult ; Female ; Gastrointestinal Motility ; Humans ; Male ; Manometry
Departments: Katedra za internu medicinu
Depositing User: Boris Čičovački
Status: Published
Creators:
CreatorsEmail
Jurčić, DraganUNSPECIFIED
Bilić, AnteUNSPECIFIED
Schwarz, DraganUNSPECIFIED
Luetić, KrešimirUNSPECIFIED
Marušić, MarinkoUNSPECIFIED
Včev, AleksandarUNSPECIFIED
Gabrić, MaruškaUNSPECIFIED
Špoljarić, LjubicaUNSPECIFIED
Date: September 2008
Date Deposited: 14 Nov 2008
Last Modified: 23 Sep 2011 16:10
Subjects: /
Related URLs:
    URI: http://medlib.mef.hr/id/eprint/518

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