Repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

The place and role of serologic methods in detecting Helicobacter pylori infection

Marušić, Marinko and Presečki, Vladimir and Katičić, Miroslava and Dominis, Mara and Kalenić, Smilja (2006) The place and role of serologic methods in detecting Helicobacter pylori infection. Collegium antropologicum, 30 (3). pp. 529-533. ISSN 0350-6134 (Print)

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    Croatian abstract

    Cilj nam je bio na temelju utvrđenih vrijednosti osjetljivosti i specifičnosti metoda ELISA (imunoenzimski test) i reakcije vezanja komplementa odrediti mjesto i značenje seroloških metoda u otkrivanju infekcije Helicobacter pylori (H. pylori). U ispitivanje je bilo uključeno 549 bolesnika, a navedene serološke metode su uspoređene s invazivnim metodama (CLO test, izolacija, histološki pregled). Osjetljivost seroloških metoda premašila je 90%, dok je specifičnost bila približno 80%. Ovim radom je dokazana vrijednost, pouzdanost i opravdanost uporabe seroloških postupaka u otkrivanju infekcije H. pylori.

    English abstract

    The aim of the study was to determine the place and role of serologic methods in detecting Helicobacter pylori (H. pylori) infection, on the basis of estimated enzyme-linked immunosorbent assay (ELISA) and complement fixation test (CFT) sensitivity and specificity. A total of 549 patients were included in the study. ELISA and CFT as serologic methods were compared with invasive methods (rapid urease test--CLO test, culture, histology). The sensitivity of serologic methods was above 90%, and their specificity was around 80%. Study results confirmed the value, reliability and usefulness of serologic methods in the detection of H. pylori infection.

    Item Type: Article
    MeSH: Antibodies, Bacterial - isolation & purification ; Complement Fixation Tests - methods ; Enzyme-Linked Immunosorbent Assay - methods ; Helicobacter Infections - diagnosis ; Helicobacter pylori - immunology ; Adult ; Female ; Humans ; Male ; Middle Aged ; Sensitivity and Specificity
    Divisions: Katedra za internu medicinu
    Katedra za patologiju
    Depositing User: Boris Čičovački
    Status: Published
    Creators:
    CreatorsEmail
    Marušić, Marinko
    Presečki, Vladimir
    Katičić, Miroslava
    Dominis, Mara
    Kalenić, Smilja
    Date: September 2006
    Date Deposited: 14 Oct 2008
    Last Modified: 23 Sep 2011 18:10
    Subjects: /
    Related URLs:
      URI: http://medlib.mef.hr/id/eprint/469

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