Aortic valve replacement in a patient with severe hemophilia

Gašparović, Hrvoje and Zupančić-Salek, Silva and Brida, Vojtjeh and Dulić, Grgur and Jelić, Ivan (2007) Aortic valve replacement in a patient with severe hemophilia. Collegium antropologicum, 31 (1). pp. 355-357. ISSN 0350-6134 (Print)

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Abstract

Hemophilia A is an inherited bleeding disorder characterized by factor VIII deficiency. The basis for insufficient hemostasis lies within inadequate amplification of factor Xa production with the undersupplied factor VIII. We report on a young patient with critical aortic stenosis bearing all the clinical stigmata of severe hemophilia, in whom aortic valve replacement was performed with a tissue valve in order to avoid the need for long term anticoagulation.

Abstract in Croatian

Hemofilija A je nasljedni poremećaj koagulacije koji je karakteriziran nedostatkom faktora VIII. U podlozi manjkavog hemostatskog potencijala je neadekvatna amplifikacija faktora Xa sa faktorom VIII. Ovaj prikaz slučaja fokusira se na mladog bolesnika sa kritičnom stenozom aortalne valvule koji boluje od teškog oblika hemofilije A. Strategija kirurškog liječenja bazirala se na zamjeni aortalne valvule sa tkivnom protezom kako bi se izbjegla dugoročna antikoagulacija.

Item Type: Article
MeSH: Aortic Valve - surgery ; Aortic Valve Stenosis - surgery ; Heart Valve Prosthesis Implantation - methods ; Hemophilia A - blood ; Factor VIII - administration & dosage ; Humans ; Male ; Middle Aged
Departments: Katedra za kirurgiju
Depositing User: Boris Čičovački
Status: Published
Creators:
CreatorsEmail
Gašparović, HrvojeUNSPECIFIED
Zupančić-Salek, SilvaUNSPECIFIED
Brida, VojtjehUNSPECIFIED
Dulić, GrgurUNSPECIFIED
Jelić, IvanUNSPECIFIED
Date: March 2007
Date Deposited: 13 Oct 2008
Last Modified: 23 Sep 2011 16:10
Subjects: /
Related URLs:
    URI: http://medlib.mef.hr/id/eprint/456

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