Repozitorij Medicinskog fakulteta Sveučilišta u Zagrebu

Aortic valve replacement in a patient with severe hemophilia

Gašparović, Hrvoje and Zupančić-Salek, Silva and Brida, Vojtjeh and Dulić, Grgur and Jelić, Ivan (2007) Aortic valve replacement in a patient with severe hemophilia. Collegium antropologicum, 31 (1). pp. 355-357. ISSN 0350-6134 (Print)

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    Croatian abstract

    Hemofilija A je nasljedni poremećaj koagulacije koji je karakteriziran nedostatkom faktora VIII. U podlozi manjkavog hemostatskog potencijala je neadekvatna amplifikacija faktora Xa sa faktorom VIII. Ovaj prikaz slučaja fokusira se na mladog bolesnika sa kritičnom stenozom aortalne valvule koji boluje od teškog oblika hemofilije A. Strategija kirurškog liječenja bazirala se na zamjeni aortalne valvule sa tkivnom protezom kako bi se izbjegla dugoročna antikoagulacija.

    English abstract

    Hemophilia A is an inherited bleeding disorder characterized by factor VIII deficiency. The basis for insufficient hemostasis lies within inadequate amplification of factor Xa production with the undersupplied factor VIII. We report on a young patient with critical aortic stenosis bearing all the clinical stigmata of severe hemophilia, in whom aortic valve replacement was performed with a tissue valve in order to avoid the need for long term anticoagulation.

    Item Type: Article
    MeSH: Aortic Valve - surgery ; Aortic Valve Stenosis - surgery ; Heart Valve Prosthesis Implantation - methods ; Hemophilia A - blood ; Factor VIII - administration & dosage ; Humans ; Male ; Middle Aged
    Divisions: Katedra za kirurgiju
    Depositing User: Boris Čičovački
    Status: Published
    Creators:
    CreatorsEmail
    Gašparović, Hrvoje
    Zupančić-Salek, Silva
    Brida, Vojtjeh
    Dulić, Grgur
    Jelić, Ivan
    Date: March 2007
    Date Deposited: 13 Oct 2008
    Last Modified: 23 Sep 2011 18:10
    Subjects: /
    Related URLs:
      URI: http://medlib.mef.hr/id/eprint/456

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