Isolated cranial nerve palsies in multiple sclerosis

Zadro, Ivana and Barun, Barbara and Habek, Mario and Brinar, Vesna V. (2008) Isolated cranial nerve palsies in multiple sclerosis. Clinical Neurology and Neurosurgery, 110 (9). pp. 886-888. ISSN 0303-8467

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Official URL: https://doi.org/10.1016/j.clineuro.2008.02.009

Abstract

Data on patients with multiple sclerosis and cranial nerve involvement as a presenting sign or a sign of disease exacerbation were retrospectively analyzed. Isolated cranial nerve involvement was present in 10.4% out of 483 patients, either as a presenting symptom (7.3%) or a symptom of disease relapse (3.1%). Trigeminal nerve was most frequently involved, followed by facial, abducens, oculomotor and cochlear nerves. Only 54% of patients had brainstem MRI lesion that could explain the symptoms. As multiple sclerosis is a disease characterized by multiple neurological symptoms, while early diagnosis and therapy are critical for the prognosis and course of the disease, the diagnosis of multiple sclerosis should be considered in young adults with cranial nerve involvement.

Item Type:

Article

MeSH:

Cranial Nerve Diseases - diagnosis - etiology ; Multiple Sclerosis - complications - diagnosis ; Adolescent ; Adult ; Brain - pathology ; Child ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Paralysis - etiology ; Recurrence ; Retrospective Studies ; Spinal Cord - pathology ; Young Adult

Departments:

Katedra za neurologiju

Depositing User:

Boris Čičovački

Status:

Published

Creators: