Serum immunoglobulins IgG, IgA and IgM in patients with oral lichen ruber

Biočina-Lukenda, Dolores and Cekić-Arambašin, Ana and Markeljević, Jasenka and Buković, Dino (2008) Serum immunoglobulins IgG, IgA and IgM in patients with oral lichen ruber. Collegium antropologicum, 32 (1). pp. 161-163. ISSN 0350-6134 (Print)

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The aim of this study was to determine level of serum IgA, IgG and IgM in patients with OLR as indicators of humoral immunity which might reflect cell-mediated immunity. This study was conducted on 30 patients (age 60.17 +/- 11.75) with clinically and histopathologically confirmed diagnosis of OLR and 30 healthy controls (age 56.16 +/- 11.82) Determination of serum IgA, IgG and IgM was performed by use of standard laser nephelometry in both patients and controls. Statistical analysis was done using Mann-Whitney U test and the level of significance was determined as p values lower than 0.05. Serum IgA and IgM in patients with OLR were significantly increased in comparison to the control group, while serum IgG levels were higher in patients with OLR but they did not reach significance. We might conclude that elevated levels of serum IgA and IgM show that humoral immunity is implicated in the pathogenesis of OLR.

Item Type: Article
MeSH: Immunoglobulins - blood ; Lichen Planus, Oral - immunology ; Female ; Humans ; Immunoglobulin A - blood ; Immunoglobulin G - blood ; Immunoglobulin M - blood ; Male ; Middle Aged
Departments: Katedra za internu medicinu
Depositing User: Boris Čičovački
Status: Published
Biočina-Lukenda, DoloresUNSPECIFIED
Cekić-Arambašin, AnaUNSPECIFIED
Markeljević, JasenkaUNSPECIFIED
Date: March 2008
Date Deposited: 03 Oct 2008
Last Modified: 23 Sep 2011 16:10
Subjects: /
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