Analysis and quantification of bone healing after open wedge high tibial osteotomy

Nemecek, Elena and Chiari, Catharina and Valentinitsch, Alexander and Kainberger, Franz and Hobusch, Gerhard and Kolb, Alexander and Hirtler, Lena and Trost, Carmen and Vukičević, Slobodan and Windhager, Reinhard (2019) Analysis and quantification of bone healing after open wedge high tibial osteotomy. Wiener klinische Wochenschrift, 131 (23-24). pp. 587-598. ISSN 0043-5325

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Abstract

Background: The aim of this study was to analyze radiographic imaging techniques and to quantify bone ossification in the osteotomy gap after high tibial osteotomy. ------ Material and methods: Study phase 1: high tibial osteotomy was performed on six lower extremities of human body donors and experimental X‑rays and computed tomography (CT) scans were applied. Different techniques were evaluated by three specialists for best representation of the osteotomy gap. Study phase 2: optimized radiological techniques were used for follow-up on 12 patients. The radiographs were examined by 3 specialists measuring 10 different parameters. The CT scans were analyzed with semiautomatic computer software for quantification of bone ossification. ----- Results: The osteotomy gap was best represented in 30° of flexion in the knee and 20° internal rotation of the leg. There were significant changes of the medial width over time (p < 0.019) as well as of the length of fused osteotomy, the Schröter score, sclerosis, trabecular structure and zone area measurements. Sclerosis, medial width of the osteotomy and area measurements were detected as reproducible parameters. Bone mineral density was calculated using CT scans, showing a significantly higher value 12 weeks postoperatively (112.5 mg/cm3) than at baseline (54.6 mg/cm3). The ossification of the gap was visualized by color coding. ----- Conclusion: Sclerosis and medial width of the osteotomy gap as well as area measurements were determined as reproducible parameters for evaluation of bone healing. Quantification of bone ossification can be calculated with CT scans using a semiautomatic computer program and should be used for research in bone healing.

Item Type: Article
Additional Information: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes weremade.
MeSH: Fracture Healing ; Fractures, Bone ; Humans ; Knee Joint ; Osteotomy / methods ; Tibia / surgery
Departments: Katedra za anatomiju i kliničku anatomiju
Depositing User: Kristina Berketa
Status: Published
Creators:
CreatorsEmail
Nemecek, ElenaUNSPECIFIED
Chiari, CatharinaUNSPECIFIED
Valentinitsch, AlexanderUNSPECIFIED
Kainberger, FranzUNSPECIFIED
Hobusch, GerhardUNSPECIFIED
Kolb, AlexanderUNSPECIFIED
Hirtler, LenaUNSPECIFIED
Trost, CarmenUNSPECIFIED
Vukičević, SlobodanUNSPECIFIED
Windhager, ReinhardUNSPECIFIED
Date: December 2019
Date Deposited: 21 Aug 2020 08:14
Last Modified: 21 Aug 2020 08:14
Subjects: /
Related URLs:
URI: http://medlib.mef.hr/id/eprint/3604

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