The effect of delayed anti-NMDAR encephalitis recognition on disease outcome

Šulentić, Vlatko and Petelin Gadže, Željka and Derke, Filip and Santini, Marija and Bažadona, Danira and Nanković, Sibila (2018) The effect of delayed anti-NMDAR encephalitis recognition on disease outcome. Journal of Neurovirology, 24 (5). pp. 638-641. ISSN 1355-0284

PDF - Accepted Version Download (1MB)

Abstract

Anti-NMDA receptor encephalitis is an acute form of brain inflammation that is potentially lethal but has a high probability for recovery with treatment. Although the clinical picture of anti-NMDAR encephalitis is usually recognizable due to its relatively well-known symptoms, the disorder can sometimes present itself in an unpredictable and atypical way. In this case report, we wish to present the influence of different delay times prior to the establishment of diagnosis. Thus, our first patient was diagnosed with anti-NMDAR encephalitis 4 years after the initial symptoms, the second one after 8 years, and the third one after 13 months. The outcomes of the three presented patients indicate the importance of being aware of many clinical presentations of this disorder, as its early diagnosis greatly affects the outcome and may reduce permanent damage, especially in cognitive functions.

Actions (login required)

View Item

Downloads