Primary dural lymphoma mimicking meningioma: a clinical and surgical case report

Raguž, Marina and Mudrovčić, Yannick and Dlaka, Domagoj and Almahariq, Fadi and Romić, Dominik and Tomasović-Lončarić, Čedna and Müller, Danko and Marčinković, Petar and Kaštelančić, Anđelo and Chudy, Darko (2018) Primary dural lymphoma mimicking meningioma: a clinical and surgical case report. Journal of Surgical Case Reports, 2018 (8). rjy189. ISSN 2042-8812

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Abstract

INTRODUCTION: Primary central nervous system lymphoma and its subtype, primary dural lymphoma, are types of non-Hodgkin's lymphoma that only occur in the central nervous system without any dissemination. They are extremely rare cases of extra nodal lymphomas accounting for 1--5% of intracranial tumors. ----- CASE REPORT: We present a patient diagnosed with primary dural lymphoma in right frontal brain region who underwent surgical resection. Histopathological analysis revealed diffuse B-type large cell non-Hodgkin lymphoma. Patient underwent four cycles of R-CHOP and intrathecal methotrexate protocol. Six months postoperative, no signs of newly onset infiltration were present. ----- DISCUSSION: Primary dural lymphoma most likely presents with unusual radiological signs, which can easily be mistaken for meningioma, the main differential diagnosis. A thorough immunological, histopathological and clinical patients profile should be conducted in order to establish the certainty of diagnosis. Although there are few treatment options: surgery, radiotherapy or chemotherapy, there is no established treatment protocol.

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