Impact of pre-pregnancy BMI on blood glucose levels in pregnancy and on the anthropometry of newborns – preliminary insights from the Croatian Islands' Birth Cohort Study (CRIBS)

Fuchs, Nives and Novokmet, Natalija and Lela, Ivana and Zajc Petranović, Matea and Havaš Aguštin, Dubravka and Šarac, Jelena and Carić, Tonko and Dolanc, Ivan and Kurelović, Deni and Škrabić, Veselin and Orehovec, Biserka and Romić, Željko and Janković, Stipan and Musić Milanović, Sanja and Delale, Eva Anđela and Cameron, Noel and Missoni, Saša (2018) Impact of pre-pregnancy BMI on blood glucose levels in pregnancy and on the anthropometry of newborns – preliminary insights from the Croatian Islands' Birth Cohort Study (CRIBS). Collegium Antropologicum, 42 (2). pp. 89-93. ISSN 0350-6134

PDF - Published Version Download (785kB)

Abstract

The aim of this study was to investigate the relationship between pre-pregnancy body mass index (BMI) and fasting blood glucose level in pregnancy on the anthropometry of newborns. The sample consisted of 171 healthy pregnant women and their newborns from the Croatian Islands’ Birth Cohort Study. Peripheral blood of pregnant women was taken in the second trimester and fasting glucose values >5.1 mmol/l were considered elevated. Anthropometric variables (body weight, height and waist circumference) were measured according to the International Biological Program. Pre-pregnancy BMI and fasting glucose levels during pregnancy were significantly positively correlated (p<0,01), as were pre-pregnancy BMI and birth weight (p<0,05), length (p<0,01), and head circumference (p<0,05) of the newborns. Hyperglycaemic women gave birth to significantly heavier newborn girls then normal glycaemic women (p<0.05). In conclusion, there was a positive correlation between pre-pregnancy BMI, fasting glucose during pregnancy and the anthropometry of newborns in this study.

Abstract in Croatian

U ovoj pilot studiji pod nazivom »Kohortna studija rođenih na istočnojadranskim otocima« (CRIBS) koja je još u tijeku, analizirani uzorak je obuhvatio 171 zdravu trudnicu te njihovu novorođenčad s područja Splitsko – Dalmatinske županije, točnije hrvatskih otoka Brača i Hvara te područja grada Splita i bliže okolice. Cilj ovog rada bio je istražiti utjecaj indeksa tjelesne mase (ITM) prije trudnoće i razine glukoze u trudnoći na antropometrijska obilježja novorođenčeta (porođajnu težinu, porođajnu duljinu i opseg glave). Antropometrijske varijable majke (tjelesna masa, tjelesna visina i opseg struka) mjerene su prema metodama opisanima u Praktikumu biološke antropometrije (1975.), izrađenima u skladu s protokolom International Biological Programme. U okviru biokemijskih analiza trudnicama su izuzeti uzorci periferne krvi u drugom trimesteru trudnoće. Izmjerene vrijednosti glukoze >5.1 mmol/L smatrane su povišenima. Statističke analize provedene su pomoću programa SPSS10.0 for Windows. Preliminarni rezultati pokazali su značajnu korelaciju porasta glukoze u krvi trudnica s povećanim indeksom tjelesne mase prije trudnoće (p<0,01) kao i značajnu korelaciju povećanog indeksa tjelesne mase prije trudnoće s većom porođajnom težinom (p<0,05) porođajnom duljinom (p<0,01) i opsegom glave (p<0,05) novorođenčadi. Utvrđena je i povezanost povišene vrijednosti glukoze s povećanom porođajnom težinom ženske novorođenčadi (p<0.05). Iz prikazanih rezultata vidljiv je trend rasta antropometrijskih osobina novorođenčeta s povećanim vrijednostima glukoze u krvi trudnica i indeksom tjelesne mase prije trudnoće. Temeljem dobivenih preliminarnih rezultata možemo zaključiti da postoji utjecaj tjelesnog i zdravstvenog statusa (prehrambenog) trudnica na antropometrijske značajke novorođenčadi.

Actions (login required)

View Item

Downloads