From ataxia to diagnosis of askin tumor – a case report

Bašković, Marko and Župančić, Božidar and Žganjer, Mirko and Nikolić, Igor and Ježek, Davor and Čizmić, Lucija (2018) From ataxia to diagnosis of askin tumor – a case report. Acta Medica (Hradec Kralove, Czech Republic), 61 (2). pp. 60-64. ISSN 1211-4286

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Peripheral primitive neuroectodermal tumors (pPNET) are a group of extremely rare, aggressive, malignant tumors that are most often found in the thorax (Askin tumor), abdomen, pelvis, extremities and less frequently in the head and neck. The most important prognostic factor is the stage of the tumor. Significant progress both in surgery and in neoadjuvant and adjuvant chemotherapy and radiotherapy, as well as the improvement in diagnosis by cytogenetic and immunohistochemical analysis, should improve the survival rate. We report a case of a 14-year-old girl, with ataxic gait, cardiopulmonary compensated, without respiratory symptoms, who was referred to our hospital for further examination and treatment of newly discovered tumor of the left hemithorax. After a detailed radiological and laboratory investigation, next step was an extensive thoraco-neurosurgical surgery. After histopathological, cytological and molecular analysis, a diagnosis of Askin tumor was made.

Item Type: Article
Additional Information: © 2018 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
MeSH: Adolescent ; Ataxia/etiology ; Bone Neoplasms/diagnosis ; Female ; Humans ; Sarcoma, Ewing/diagnosis
Departments: Katedra za histologiju i embriologiju
Katedra za kirurgiju
Depositing User: Anja Majstorović
Status: Published
Bašković, MarkoUNSPECIFIED
Župančić, BožidarUNSPECIFIED
Date: 2018
Date Deposited: 14 Jun 2019 08:20
Last Modified: 25 Aug 2020 07:00
Subjects: /
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