Kliničke preporuke za dijagnozu, liječenje i praćenje bolesnika oboljelih od raka nepoznata primarnog podrijetla [Clinical recommendations for diagnosis, treatment and monitoring of patients with cancer of unknown primary site]

Bišof, Vesna and Juretić, Antonio and Trivanović, Dragan and Dobrila Dintinjana, Renata and Šarčević, Božena and Jakić-Razumović, Jasminka and Ban, Marija and Bošković, Lidija and Petrić Miše, Branka and Bura, Miljenko and Stančić-Rokotov, Dinko (2015) Kliničke preporuke za dijagnozu, liječenje i praćenje bolesnika oboljelih od raka nepoznata primarnog podrijetla [Clinical recommendations for diagnosis, treatment and monitoring of patients with cancer of unknown primary site]. Liječnički vjesnik, 137 (3-4). pp. 65-69. ISSN 0024-3477

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Abstract

Cancer of unknown primary (CUP) site comprises very heterogeneous group of various malignant tumors presented in metastatic phase of the disease. Diagnosis is set when primary site remains unidentified after a thorough diagnostic evaluation in patients with histologically proven malignant metastatic disease. Despite poor prognosis in most patients, favorable prognostic clinical entities have been recognized constituting the most important group of patients for oncological treatment. The following text presents the clinical guidelines in order to standardize the diagnosis, treatment and follow-up of patients with cancer of unknown primary site in the Republic of Croatia.

Abstract in Croatian

Rak nepoznata primarnog podrijetla obuhvaća vrlo heterogenu skupinu različitih malignih tumora koji se prezentiraju u metastatskoj fazi bolesti. Dijagnoza se postavlja na temelju patohistološke potvrde maligne bolesti uz nemogućnost dokaza postojanja primarnog tumora nijednom dostupnom dijagnostičkom metodom. Iako je općenito loše prognoze, prepoznati su prognostički povoljni klinički entiteti koji čine temeljnu skupinu bolesnika za aktivno onkološko liječenje. U tekstu koji slijedi sadržane su kliničke upute s ciljem standardizacije dijagnostičkih postupaka, liječenja i praćenja bolesnika s nepoznatim primarnim rakom u Republici Hrvatskoj.

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