The incidence of hyperechoic prostate cancer in transrectal ultrasound-guided biopsy specimens

Spajić, Borislav and Čupić, Hrvoje and Tomas, Davor and Štimac, Goran and Krušlin, Božo and Kraus, Ognjen (2007) The incidence of hyperechoic prostate cancer in transrectal ultrasound-guided biopsy specimens. Urology, 70 (4). pp. 734-737. ISSN 0090-4295 (Print) 1527-9995 (Electronic)

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Abstract

OBJECTIVES: To estimate the incidence of transrectal ultrasound (TRUS) hyperechoic lesions and of hyperechoic prostate cancer in TRUS-guided biopsy specimens. ----- METHODS: We prospectively studied 200 patients with total prostate-specific antigen values less than 20 ng/mL and/or positive results on digital rectal examination who had undergone TRUS-guided prostate biopsy. Each patient underwent laterally directed systemic six-core biopsy plus cores from abnormal TRUS lesions and rectally palpable lesions. Six to 10 biopsy cores were obtained from each patient. ----- RESULTS: Hyperechoic lesions were found in 19 patients (9.5%), hypoechoic in 83 (41.5%), and isoechoic in 98 (49.0%). Prostate cancer was diagnosed in 33.0% of study patients. Isoechoic findings on TRUS were recorded in 31.8% of patients diagnosed with prostate cancer, whereas 60.6% of cancers had hypoechoic and 7.6% hyperechoic lesions. There was no significant difference in the mean Gleason score between isoechoic cancers (mean 5.4) and hypoechoic cancers (mean 5.6). However, hyperechoic cancers had a mean Gleason score of 7.0, which was higher when compared with isoechoic and hypoechoic cancers. ----- CONCLUSIONS: Biopsy of hyperechoic lesions was positive for prostate cancer in a higher percentage of patients than previously reported in the literature, and Gleason score of these cancers was higher when compared with isoechoic and hypoechoic cancers.

Item Type: Article
MeSH: Biopsy, Needle ; Ultrasonography, Interventional ; Prostatic Neoplasms - diagnosis - pathology - ultrasonography ; Aged ; Humans ; Male ; Middle Aged ; Prostate - pathology ; Prostate-Specific Antigen - blood
Departments: Katedra za patologiju
Depositing User: Lea Škorić
Status: Published
Creators:
CreatorsEmail
Spajić, BorislavUNSPECIFIED
Čupić, HrvojeUNSPECIFIED
Tomas, DavorUNSPECIFIED
Štimac, GoranUNSPECIFIED
Krušlin, BožoUNSPECIFIED
Kraus, OgnjenUNSPECIFIED
Date: October 2007
Date Deposited: 04 Dec 2007
Last Modified: 23 Sep 2011 16:10
Subjects: /
Related URLs:
    URI: http://medlib.mef.hr/id/eprint/301

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