Progression of conjunctival primary acquired melanosis (PAM) to widely spreaded malignant melanoma [Progresija primarne melanoze spojnice u rasprostranjeni maligni melanom spojnice]

Jandroković, Sonja and Popović-Suić, Smiljka and Juri Mandić, Jelena and Kuzman, Tomislav and Škegro, Ivan and Barišić Kutija, Marija and Masnec, Sanja and Kalauz, Miro (2014) Progression of conjunctival primary acquired melanosis (PAM) to widely spreaded malignant melanoma [Progresija primarne melanoze spojnice u rasprostranjeni maligni melanom spojnice]. Collegium Antropologicum, 38 (4). pp. 1187-1190. ISSN 0350-6134

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Abstract

Primary acquired melanosis (PAM) is an acquired pigmentation of the conjunctival epithelium, a preinvasive pigmented lesion. When it is associated with cellular atypia it can lead to the developement of melanoma. We report a case report of malignant melanoma of the conjuntiva, which arrised from the conjuntival PAM. The disease was too extensive for ocular conservation, therefore exenteration was performed. This case highlights the need for regular follow-up of patients with melanocytic lesions of the ocular adnexa, and particular attention to the surgical technique, and careful follow-up to detect further disease activity.

Abstract in Croatian

Primarna melanoza spojnice je stečena pigmentcija epitela spojnice, preinvazivna pigmentna lezija. Kada se razvije stanična atipija može nastati melanom. Prikazujemo slučaj malignog melanoma spojnice koji se razvio od primarne melanoze spojnice. Bolest je bila izrazito raspostranjena, oko se nije moglo sačuvati i u svrhu liječenja je učinjena egzenteracija orbite. Ovim prikazom slučaja želimo istaknuti važnost redovitih kontrola pigmentnih lezija spojnice i očnih adneksa. Iznimno je važno obratiti pozornost na planiranje kirurške tehnike te nastaviti praćenje aktivosti bolesti redovitim kontrolama.

Item Type: Article
MeSH: Aged ; Conjunctival Neoplasms/pathology ; Conjunctival Neoplasms/surgery ; Disease Progression ; Female ; Humans ; Melanoma/diagnosis ; Melanoma/pathology ; Melanoma/surgery ; Melanosis/pathology
Departments: Katedra za oftalmologiju
Depositing User: Ana Babić
Status: Published
Creators:
CreatorsEmail
Jandroković, SonjaUNSPECIFIED
Popović-Suić, SmiljkaUNSPECIFIED
Juri Mandić, JelenaUNSPECIFIED
Kuzman, TomislavUNSPECIFIED
Škegro, IvanUNSPECIFIED
Barišić Kutija, MarijaUNSPECIFIED
Masnec, SanjaUNSPECIFIED
Kalauz, MiroUNSPECIFIED
Date: December 2014
Date Deposited: 18 Feb 2016 13:02
Last Modified: 17 Jul 2020 07:56
Subjects: /
Related URLs:
URI: http://medlib.mef.hr/id/eprint/2455

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