Gastroenteropancreatic neuroendocrine tumour arising in Meckel's diverticulum coexisting with colon adenocarcinoma

Katalinić, Darko and Šantek, Fedor and Juretić, Antonio and Škegro, Dinko and Pleština, Stjepko (2014) Gastroenteropancreatic neuroendocrine tumour arising in Meckel's diverticulum coexisting with colon adenocarcinoma. World Journal of Surgical Oncology, 12. p. 358. ISSN 1477-7819

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Although colon cancer is the third most common cause of cancer-related death worldwide, the prevalence of gastroenteropancreatic neuroendocrine tumours (GEP-NETs) remains rare. To date, very few cases of GEP-NETs within Meckel's diverticulum and synchronous colorectal cancer have been reported. Although the coexistence of these two tumour types is uncommon, it is important to be aware of their disease patterns. We present a rare case of a patient with an intestinal GEP-NET arising in Meckel's diverticulum coexisting with metastatic colon adenocarcinoma, and we discuss the clinical manifestations and the diagnostic procedures and treatment modalities used. This case report underlines the importance of being aware of this particular coexistence, as well as the unlikely metastatic spread of GEP-NETs and the importance of a multidisciplinary approach to cancer treatment. Finally, individualizing the treatment according to the stages of the primaries will result in durable cancer control, particularly in synchronous double malignancy.

Item Type: Article
Additional Information: © 2014 Katalinic et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.
MeSH: Adenocarcinoma/secondary ; Adenocarcinoma/surgery ; Colonic Neoplasms/pathology ; Colonic Neoplasms/surgery ; Humans ; Intestinal Neoplasms/secondary ; Intestinal Neoplasms/surgery ; Male ; Meckel Diverticulum/pathology ; Meckel Diverticulum/surgery ; Middle Aged ; Neoplasm Staging ; Neoplasms, Multiple Primary/pathology ; Neoplasms, Multiple Primary/surgery ; Neuroendocrine Tumors/secondary ; Neuroendocrine Tumors/surgery ; Pancreatic Neoplasms/secondary ; Pancreatic Neoplasms/surgery ; Prognosis ; Stomach Neoplasms/secondary ; Stomach Neoplasms/surgery
Departments: Katedra za radiologiju i opću kliničku onkologiju
Depositing User: Marijan Šember
Status: Published
Katalinić, DarkoUNSPECIFIED
Juretić, AntonioUNSPECIFIED
Pleština, StjepkoUNSPECIFIED
Date: 27 November 2014
Date Deposited: 12 Feb 2016 11:56
Last Modified: 17 Jul 2020 08:14
Subjects: /
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