Galešić, Krešimir and Ljubanović, Danica and Horvatić, Ivica (2013) Treatment of renal manifestations of ANCA-associated vasculitis. Journal of Nephropathology, 2 (1). pp. 6-19. ISSN 2251-8363
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Abstract
CONTEXT: Vasculitis is a clinicopathological entity characterized by inflammation and necrosis of blood vessels. ----- EVIDENCE ACQUISITIONS: Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science have been searched. ----- RESULTS: Two major autoantigens for ANCA are myeloperoxidase (MPO) and proteinase 3 (PR3), which are proteins in the primary granules of neutrophils and in the lysosomes of monocytes. They are expressed in mature neutrophils of patients with ANCA, while absent in healthy subjects. ----- CONCLUSIONS: The kidney is the most commonly affected vital organ in ANCA-associated vasculitis, and patient outcomes are largely determined by the severity of renal disease at diagnosis and by its response to treatment.
| Item Type: | Article | ||||||||
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| Additional Information: | This work is licensed under a Creative Commons Attribution 4.0 License. Copyright © 2015 by Journal of Nephropathology (JNP) Society of Diabetic Nephropathy Prevention | ||||||||
| Departments: | Katedra za internu medicinu Katedra za patologiju |
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| Depositing User: | Marijan Šember | ||||||||
| Status: | Published | ||||||||
| Creators: |
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| Date: | January 2013 | ||||||||
| Date Deposited: | 16 Dec 2015 13:32 | ||||||||
| Last Modified: | 13 Jul 2020 08:07 | ||||||||
| Subjects: | / | ||||||||
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| URI: | http://medlib.mef.hr/id/eprint/2354 |
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