Primary malignant fibrous histiocytoma of the spleen: recurrence eight years after splenectomy - report of a case and literature review [Primarni maligni fibrozni histiocitom slezene recidiv osam godina nakon splenektomije]

Rakić, Mislav and Pogorelić, Zenon and Lambaša, Smiljka and Patrlj, Leonardo and Perko, Zdravko and Rakić, Mladen and Mrklić, Ivana and Jukić, Miro (2013) Primary malignant fibrous histiocytoma of the spleen: recurrence eight years after splenectomy - report of a case and literature review [Primarni maligni fibrozni histiocitom slezene recidiv osam godina nakon splenektomije]. Collegium Antropologicum, 37 (3). pp. 1007-1010. ISSN 0350-6134

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Abstract

Primary intraabdominal malignant mesenchymal tumors are very rare. There are just few cases of intraabdominal visceral malignant fibrous histiocytoma in the literature. We report a case of primary malignant fibrous histiocytoma of the spleen in a 57-year-old man, with a recurrence eight years after the splenectomy. After the initial surgery the patient was without complaints, and refused to receive chemotherapy or radiotherapy. Eight years after the surgery the patient reported due to general weakness and malaise when the diagnosis of disease relapse was established. Radical surgery was performed although the tumor involved large curvature of the stomach, left crus of the diaphragm, splenic flexure of the colon and tail of pancreas. Four months after the surgery patient died. To the best of our knowledge, to date, only 18 cases have been reported in the literature, describing malignant fibrous histiocytoma of the spleen.

Abstract in Croatian

Primarni intraabdominalni mezenhimski tumori su vrlo rijetki. U literaturi postoji svega nekoliko opisanih slučajeva malignog fibroznog histiocitoma koji zahvaća visceralne intraabdominalne organe. Prikazujemo slučaj 57-godišnjeg bolesnika sa primarnim malignim fibroznim histiocitomom slezene, te recidivom 8 godina nakon splenektomije. Nakon primarne operacije bolesnik se dobro osjećao, bio je bez tegoba, te je odbio primati kemoterapiju i radioterapiju. Osam godina nakon operacije bolesnik se javio liječniku zbog opće slabosti i malaksalosti te mu je dijagnostičkom obradom utvrđen recidiv bolesti. Učinjen je radikalni operacijski zahvat iako je proces zahvatio veliku krivinu želuca, lijevi dio ošita, lijenalnu fleksuru debelog crijeva i rep gušterače. Četiri mjeseca nakon operacije bolesnik je umro. Prema našim saznanjima, do danas je u literaturi objavljeno samo 18 slučajeva koji opisuju maligni fibrozni histiocitom slezene.

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