Lower limb salvage surgery: modular endoprosthesis in bone tumour treatment

Orlić, Dubravko and Smerdelj, Miroslav and Kolundžić, Robert and Bergovec, Marko (2006) Lower limb salvage surgery: modular endoprosthesis in bone tumour treatment. International Orthopaedics, 30 (6). pp. 458-464. ISSN 0341-2695 (Print) 1432-5195 (Electronic)

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We retrospectively analysed 90 patients who underwent "en bloc" resection and modular endoprosthesis reconstruction in the lower limbs between 1987-2003. After proximal femur resection, reconstruction was performed with a modular endoprosthesis by Howmedica (KFTR, designed by Kotz) and modular revision endoprosthesis by W. Link or Lima-Lto (Revision system, designed by Wagner). The knee joint was reconstructed with a modular endoprosthesis (Howmedica, KFTR designed by Kotz) after distal femur or proximal tibia resection. Malignant bone tumours were present in 58 patients (64.5%), benign tumours in 16 (17.8%), metastases in 8 (8.9%), tumour-like lesions in 4 (4.4 %) and non-tumour-related destruction of the femur in 4 patients (4.4%). High-grade tumours were found in the majority of malignant bone tumours (70.7%). Treatment complications, which occurred in 26 patients, were: local recurrence of the tumour, deep infection, acetabular destruction following hemiarthroplasty, recurrent dislocations of endoprosthesis, periprosthetic fracture and hardware problems. In total, 23 patients (25.6%) died due to tumours. Endoprostheses should be considered as a treatment of choice for bone tumours in the hip and knee joint region. Advances in limb salvage surgery are, and will long continue to be, a great challenge for orthopaedic oncologists of the 21st century.

Item Type: Article
MeSH: Artificial Limbs ; Bone Nails ; Bone Neoplasms - rehabilitation - surgery ; Limb Salvage - adverse effects - instrumentation - methods ; Adolescent ; Adult ; Aged ; Arthroplasty, Replacement, Hip ; Arthroplasty, Replacement, Knee ; Bone Cements - therapeutic use ; Child ; Female ; Fractures, Spontaneous - therapy ; Humans ; Male ; Middle Aged ; Prosthesis Design ; Prosthesis Failure ; Retrospective Studies
Departments: Katedra za ortopediju
Depositing User: Lea Škorić
Status: Published
Orlić, DubravkoUNSPECIFIED
Smerdelj, MiroslavUNSPECIFIED
Kolundžić, RobertUNSPECIFIED
Bergovec, MarkoUNSPECIFIED
Date: December 2006
Date Deposited: 30 Jan 2007
Last Modified: 23 Sep 2011 16:09
Subjects: /
Related URLs:
    URI: http://medlib.mef.hr/id/eprint/201

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