Tear film status in glaucoma patients [Stanje suznog filma glaukomskih pacijenata]

Jandroković, Sonja and Popović Suić, Smiljka and Kordić, Rajko and Kuzman, Tomislav and Petriček, Igor (2013) Tear film status in glaucoma patients [Stanje suznog filma glaukomskih pacijenata]. Collegium Antropologicum, 37 (S1). pp. 137-140. ISSN 0350-6134

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Abstract

The purpose of this study was to determine the prevalence of ocular surface disease symptoms and the state of the tear film among patients with glaucoma who are receiving topical intraocular pressure lowering monotherapy. 62 responders were divided in 2 groups: 32 glaucoma patients and 30 healthy individuals. Tear film break-up time (TBUT), Schirmer 1 testing and ocular surface disease questionnaire were performed in both groups. 50% glaucoma patients and 25% control group participants had dry eye symptoms. Advanced disorder in TBUT was found in seven 21.9% glaucoma patients and was not found in the control group. Basal tear secretion measured by Schirmer 1 testing was found reduced in 87% of glaucoma patients and in 16.7% control group patients. Glaucoma patients on topical intraocular pressure lowering monotherapy showed a significantly higher prevalence of ocular surface disease symptoms, significantly reduced basal tear secretion and destabilisation of tear film in comparison with healthy volunteers.

Abstract in Croatian

Cilj studije je bilo određivanje pojavnosti simptoma suhog oka i stanja suznog filma u glaukomskih bolesnika koji su liječeni antiglaukomskim lijekovima u obliku kapljica. Glaukomski pacijenti su primali samo jednu vrstu kapi. U istraživanju je sudjelovalo 62 ispitanika koji su bili podijeljeni u dvije skupine: 32 glaukomska ispitanika i 30 zdravih ispitanika kontrolne skupine. Vrijeme pucanja suznog filma (TBUT Tear film break-up time), Schirmer 1 test i standardizirani upitnik o simptomima suhog oka provedeni su u obje skupine ispitanika. 50% glaukomskih ispitanika i 25% ispitanika kontrolne skupine imali su simptome suhog oka. Uznapredovala disfunkcija suznog filma (skraćeno vrijeme pucanja suznog filma – TBUT) ustanovljena je samo u skupini glaukomskih ispitanika (21,9%). Reduciranu bazalnu sekreciju mjerenu Schirmer 1 testom imalo je 87% ispitanika glaukomske skupine i 16,7% ispitanika kontrolne skupine. Glaukomski pacijenti liječeni monoterapijom u obliku kapi imali su značajno više simptoma povezanih sa suhoćom površine oka, sniženu bazalnu sekreciju suza kao i disfunkciju suznog filma u odnosu na kontrolnu skupinu zdravih ispitanika.

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