Comparative study of antibacterial and antifungal effects of rigid gas permeable contact lens disinfecting solutions [Komparativna studija antibakterijskih i antigljivičnih svojstava tekućina za dezinfekciju polutvrdih kontaktnih leća]

Kuzman, Tomislav and Barišić Kutija, Marija and Kordić, Rajko and Popović-Suić, Smiljka and Jandroković, Sonja and Škegro, Ivan and Pokupec, Rajko (2013) Comparative study of antibacterial and antifungal effects of rigid gas permeable contact lens disinfecting solutions [Komparativna studija antibakterijskih i antigljivičnih svojstava tekućina za dezinfekciju polutvrdih kontaktnih leća]. Collegium Antropologicum, 37 (S. 1). pp. 127-131. ISSN 0350-6134

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Abstract

The aim of this study was to compare antimicrobial efficacy of rigid contact lens disinfecting solutions. We tested five commercially available solutions: Unique pH (Alcon Laboratories), Boston Advance (Polymer Technology Corp.), Nitilens Conditioner GP (Avizor), Total Care (AMO), Boston Simplus (Bausch&Lomb). Their efficacy to disinfect saline solution experimentally contaminated with American Type Culture Collection (ATCC): Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 90028) and Staphylococcus epidermidis (isolated from our laboratory) was tested. All tested solutions reduced concentrations of bacteria and fungi below 1000 CFU/mL (Colony forming unit; reduction by 3 log and 1 log, respectively) after the 8 hours period. Overall, all contact lens care solutions showed good disinfecting activity against tested bacteria and fungi, with more variation in their antifungal than in antibacterial efficacy. Results of our study might be valuable when selecting appropriate solutions for non-compliant contact lens wearers.

Abstract in Croatian

Cilj našeg istraživanja je bila usporedba antibakterijskih i antigljivičnih svojstava pet tekućina za dezinfekciju polutvrdih kontaktnih leća. Testirali smo sljedeće tekućine: Unique pH (Alcon Laboratories), Boston Advance (Polymer Technology Corp.), Nitilens Conditioner GP (Avizor), Total Care (Advanced Medical Optics), Boston Simplus (Bausch & Lomb). Testirali smo njihovu efikasnost u dezinfekciji fiziološke otopine kontaminirane sljedećim sojevima mikroorganizama American Type Culture Collection (ATCC): Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 90028) i Staphylococcus epidermidis (soj izoliran iz našeg laboratorija). Sve testirane tekućine smanjile su koncentraciju bakterija i gljivica ispod 1000 CFU/mL (Colony forming unit; smanjenje 3 log i 1 log od početne koncentracije) nakon 8-satnog dezinfekcijskog razdoblja. Međutim, postoje razlike u njihovoj dezinfekcijskoj učinkovitosti. Rezultati naše studije pokazuju kako sve testirane tekućine imaju dobar dezinfekcijski učinak protiv testiranih bakterija i gljivica, pokazujući nešto veće međusobne razlike antigljivične nego antibakterijske učinkovitosti. Uočene razlike učinkovitosti tekućina za dezinfekciju leća mogle bi doći do izražaja kod nesuradljivih nositelja kontaktnih leća, te bi rezultati ovog istraživanja mogli biti značajni kod odabira adekvatne tekućine za nesuradljive pacijente.

Item Type: Article
MeSH: Anti-Bacterial Agents/pharmacology ; Antifungal Agents/pharmacology ; Contact Lens Solutions/pharmacology ; Contact Lenses
Departments: Katedra za oftalmologiju
Depositing User: Marijan Šember
Status: Published
Creators:
CreatorsEmail
Kuzman, TomislavUNSPECIFIED
Barišić Kutija, MarijaUNSPECIFIED
Kordić, RajkoUNSPECIFIED
Popović-Suić, SmiljkaUNSPECIFIED
Jandroković, SonjaUNSPECIFIED
Škegro, IvanUNSPECIFIED
Pokupec, RajkoUNSPECIFIED
Date: April 2013
Date Deposited: 09 Jan 2014 12:54
Last Modified: 13 Jul 2020 10:49
Subjects: /
Related URLs:
URI: http://medlib.mef.hr/id/eprint/1986

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