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Optically stimulated luminescence in vivo dosimetry for radiotherapy: physical characterization and clinical measurements in (60)Co beams

Mrčela, Iva and Bokulić, Tomislav and Izewska, Joanna and Budanec, Mirjana and Fröbe, Ana and Kusić, Zvonko (2011) Optically stimulated luminescence in vivo dosimetry for radiotherapy: physical characterization and clinical measurements in (60)Co beams. Physics in Medicine and Biology, 56 (18). pp. 6065-6082. ISSN 0031-9155

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    English abstract

    A commercial optically stimulated luminescence (OSL) dosimetry system was investigated for in vivo dosimetry in radiation therapy. Dosimetric characteristics of InLight dot dosimeters and a microStar reader (Landauer Inc.) were tested in (60)Co beams. The reading uncertainty of a single dosimeter was 0.6%. The reproducibility of a set of dosimeters after a single irradiation was 1.6%, while in repeated irradiations of the same dosimeters it was found to be 3.5%. When OSL dosimeters were optically bleached between exposures, the reproducibility of repeated measurements improved to 1.0%. Dosimeters were calibrated for the entrance dose measurements and a full set of correction factors was determined. A pilot patient study that followed phantom validation testing included more than 100 measured fields with a mean relative difference of the measured entrance dose from the expected dose of 0.8% and the standard deviation of 2.5%. In conclusion, these results demonstrate that OSL dot dosimeters represent a valid alternative to already established in vivo dosimetry systems.

    Item Type: Article
    MeSH: Aluminum Oxide/chemistry ; Cobalt Radioisotopes/therapeutic use ; Humans ; Luminescent Measurements/instrumentation ; Luminescent Measurements/methods ; Optical Devices ; Radiometry/instrumentation ; Radiometry/methods ; Radiotherapy/instrumentation ; Radiotherapy/methods ; Radiotherapy Dosage ; Reproducibility of Results ; Risk Assessment/methods ; Sensitivity and Specificity
    Divisions: Katedra za radiologiju i opću kliničku onkologiju
    Depositing User: Marijan Šember
    Status: Published
    Creators:
    CreatorsEmail
    Mrčela, Iva
    Bokulić, Tomislav
    Izewska, Joanna
    Budanec, Mirjana
    Fröbe, Ana
    Kusić, Zvonko
    Date: 21 September 2011
    Date Deposited: 18 Jan 2012 13:11
    Last Modified: 18 Jan 2012 13:11
    Subjects: /
    Related URLs:
    URI: http://medlib.mef.hr/id/eprint/1440

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