Raised electrical uterine activity and shortened cervical length could predict preterm delivery in a low-risk population

Grgić, Ozren and Matijević, Ratko and Kuna, Krunoslav (2012) Raised electrical uterine activity and shortened cervical length could predict preterm delivery in a low-risk population. Archives of Gynecology and Obstetrics, 285 (1). pp. 31-35. ISSN 0932-0067

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PURPOSE: To compare diagnostic accuracy of sonographic cervical length (CL) measurement and uterine electric activity assessed by electromyography (EMG) in second trimester regarding prediction of preterm delivery (PTD). ----- METHODS: Prospective study of 308 low-risk women. Shortened CL was defined as ≤25 mm (≤5th centile), while raised EMG activity was defined as the presence of ≥20 action potentials in 20 min of assessment (≥95th centile). Outcome measures were diagnostic accuracy of both tests alone or in combination for prediction of PTD and early PTD (≤34 weeks). ----- RESULTS: The incidence of PTD was 23/308 (7.4%) while the incidence of early PTD was 9/308 (2.9%). Shortened CL and raised EMG activity were significantly related to PTD [prevalence-weighted likelihood ratio (pw-LR) 1.9, 95% CI 1.0-3.5 vs. 9.5, 95% CI 2.5-35.7], but not to early PTD (pw-LR 0.4, 95% CI 0.2-0.8 vs. 0.6, 95% CI 0.3-1.7). Significant predictive value for early PTD was found only if both tests were combined (pw-LR 4, 95% CI 1.3-14.3). ----- CONCLUSION: Shortened CL and raised EMG activity in second trimester have significant diagnostic accuracy regarding prediction of PTD in a low-risk population. However, in order to be useful as a predictor for early PTD both tests must be positive.

Item Type: Article
MeSH: Action Potentials / physiology ; Adult ; Cervical Length Measurement ; Cervix Uteri / diagnostic imaging ; Cervix Uteri / physiopathology ; Electromyography ; Female ; Humans ; Obstetric Labor, Premature / diagnosis ; Obstetric Labor, Premature / diagnostic imaging ; Predictive Value of Tests ; Pregnancy ; Pregnancy Trimester, Second ; Sensitivity and Specificity ; Young Adult
Departments: Katedra za ginekologiju i opstetriciju
Depositing User: Marijan Šember
Status: Published
Matijević, RatkoUNSPECIFIED
Kuna, KrunoslavUNSPECIFIED
Date: January 2012
Date Deposited: 17 Jan 2012 15:44
Last Modified: 08 Jul 2020 11:16
Subjects: /
Related URLs:
URI: http://medlib.mef.hr/id/eprint/1436

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